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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGAP3
All Species:
12.73
Human Site:
T321
Identified Species:
31.11
UniProt:
Q9NP61
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP61
NP_001135765.1
516
56928
T321
S
V
I
S
H
S
V
T
S
D
M
Q
T
I
E
Chimpanzee
Pan troglodytes
XP_001171224
516
56901
T321
S
G
I
S
H
S
V
T
S
D
M
Q
T
I
E
Rhesus Macaque
Macaca mulatta
XP_001107803
516
56806
T321
S
G
I
S
H
S
V
T
S
D
M
Q
T
I
E
Dog
Lupus familis
XP_848847
517
57143
T322
S
G
I
S
H
S
V
T
S
D
M
Q
T
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8S3
523
57437
E328
T
S
D
M
Q
T
I
E
Q
E
S
P
T
L
A
Rat
Rattus norvegicus
Q4KLN7
525
57652
Q330
S
D
M
Q
T
I
E
Q
E
S
P
T
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512573
489
53316
E296
M
T
D
M
Q
T
I
E
Q
E
T
P
V
L
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032507
536
58567
E340
E
M
L
V
I
E
Q
E
T
P
V
G
V
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09531
529
57893
D333
G
I
R
S
I
K
Q
D
D
V
L
T
F
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82171
395
43079
K203
G
A
R
K
L
T
T
K
S
S
G
T
L
Y
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
96.7
88.7
N.A.
80.5
80.3
N.A.
62
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
35.1
N.A.
Protein Similarity:
100
96.3
98.2
94.1
N.A.
88.9
87.8
N.A.
73.8
N.A.
N.A.
71
N.A.
N.A.
N.A.
54.6
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
40
20
N.A.
26.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
20
0
0
0
0
10
10
40
0
0
0
0
10
% D
% Glu:
10
0
0
0
0
10
10
30
10
20
0
0
0
0
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
20
30
0
0
0
0
0
0
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
40
0
20
10
20
0
0
0
0
0
0
40
0
% I
% Lys:
0
0
0
10
0
10
0
10
0
0
0
0
0
20
20
% K
% Leu:
0
0
10
0
10
0
0
0
0
0
10
0
20
20
0
% L
% Met:
10
10
10
20
0
0
0
0
0
0
40
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
10
20
0
0
0
% P
% Gln:
0
0
0
10
20
0
20
10
20
0
0
40
0
0
0
% Q
% Arg:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
10
0
50
0
40
0
0
50
20
10
0
0
0
10
% S
% Thr:
10
10
0
0
10
30
10
40
10
0
10
30
50
0
0
% T
% Val:
0
10
0
10
0
0
40
0
0
10
10
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _